Masanori Nakagawa Selected Research

Alexander Disease (Alexander's Disease)

10/2019	Towards genomic database of Alexander disease to identify variations modifying disease phenotype.
1/2018	Aberrant astrocyte Ca2+ signals "AxCa signals" exacerbate pathological alterations in an Alexander disease model.
1/2017	A novel three-base duplication, E243dup, of GFAP identified in a patient with Alexander disease.
8/2012	Clinical aspects and pathology of Alexander disease, and morphological and functional alteration of astrocytes induced by GFAP mutation.
3/2012	Late-onset Alexander disease with a V87L mutation in glial fibrillary acidic protein (GFAP) and calcifying lesions in the sub-cortex and cortex.
7/2009	The process of inducing GFAP aggregates in astrocytoma-derived cells is different between R239C and R416W mutant GFAP. A time-lapse recording study.
10/2003	A case of adult-onset Alexander disease with Arg416Trp human glial fibrillary acidic protein gene mutation.
3/2002	Autosomal dominant palatal myoclonus and spinal cord atrophy.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Masanori Nakagawa Research Topics

Disease

8	Alexander Disease (Alexander's Disease) 10/2019 - 03/2002
8	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2019 - 01/2009
8	Cognitive Dysfunction 01/2018 - 03/2007
8	Parkinson Disease (Parkinson's Disease) 01/2017 - 10/2006
7	Alzheimer Disease (Alzheimer's Disease) 01/2017 - 11/2005
6	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 06/2022 - 01/2003
6	Dementia (Dementias) 01/2018 - 11/2005
5	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2019 - 07/2009
4	Disease Progression 10/2021 - 12/2002
4	Muscular Diseases (Myopathy) 01/2017 - 12/2010
4	Myasthenia Gravis 11/2016 - 09/2005
3	Tropical Spastic Paraparesis (Tropical Spastic Paraplegia) 12/2022 - 01/2004
3	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 06/2022 - 06/2008
3	Hypertension (High Blood Pressure) 10/2021 - 01/2005
3	CADASIL 09/2020 - 01/2008
3	Stroke (Strokes) 09/2020 - 03/2005
3	Infarction (Infarctions) 01/2018 - 02/2008
3	Parkinsonian Disorders (Parkinsonism) 01/2017 - 01/2010
3	Seizures (Absence Seizure) 01/2017 - 04/2009
3	Meningitis 01/2015 - 02/2009
3	Infections 03/2011 - 01/2006
3	Peripheral Nervous System Diseases (PNS Diseases) 03/2010 - 01/2003
2	Amyloidosis 06/2022 - 01/2009
2	Hypoxia (Hypoxemia) 03/2022 - 01/2003
2	Neuromyelitis Optica (Devic's Disease) 06/2018 - 04/2011
2	Multiple Sclerosis 01/2018 - 10/2016
2	Spinal Cord Diseases 10/2017 - 08/2007
2	Neoplasms (Cancer) 09/2017 - 08/2009
2	Multiple System Atrophy 01/2016 - 06/2014
2	Progressive Bulbar Palsy (Fazio Londe Syndrome) 07/2015 - 12/2013
2	Inflammation (Inflammations) 01/2015 - 11/2009
2	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 06/2014 - 01/2007
2	Dermatomyositis (Dermatopolymyositis) 05/2014 - 01/2009
2	Muscle Weakness 12/2013 - 01/2009
2	Mood Disorders (Mood Disorder) 04/2012 - 10/2009
2	Schizophrenia (Dementia Praecox) 03/2012 - 10/2009
2	Neuroleptic Malignant Syndrome 01/2012 - 01/2011
2	Polymyositis 09/2011 - 01/2009
2	Atherosclerosis 10/2010 - 11/2009
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 03/2010 - 06/2002
2	Glioma (Gliomas) 10/2002 - 02/2002
1	Spinal Diseases (Disease, Spinal) 01/2021
1	Leukoencephalopathies 01/2020
1	Rare Diseases (Rare Disease) 10/2019
1	Inclusion Body Myositis 01/2019
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Mitochondrial Myopathies (Mitochondrial Myopathy) 01/2018
1	Hemifacial Spasm 11/2017
1	Trigeminal Neuralgia (Tic Douloureux) 11/2017
1	Meningioma (Meningiomas) 09/2017
1	Hemolytic Anemia 01/2017
1	Nervous System Diseases (Neurological Disorders) 01/2017

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2021 - 10/2002
8	Glial Fibrillary Acidic ProteinIBA 10/2019 - 03/2002
7	Biomarkers (Surrogate Marker)IBA 10/2021 - 12/2013
5	Amyloid (Amyloid Fibrils)IBA 01/2017 - 11/2005
5	SynucleinsIBA 01/2015 - 01/2012
4	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2022 - 01/2010
4	Mitochondrial DNA (mtDNA)IBA 09/2011 - 04/2002
3	SteroidsIBA 03/2022 - 08/2013
3	Myelin P0 Protein (Myelin Protein Zero)IBA 01/2021 - 01/2003
3	Prednisolone (Predate)FDA LinkGeneric 06/2018 - 01/2009
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2017 - 08/2013
3	alpha-SynucleinIBA 08/2010 - 10/2006
2	Prealbumin (Transthyretin)IBA 06/2022 - 01/2009
2	lomerizineIBA 09/2020 - 03/2009
2	DNA (Deoxyribonucleic Acid)IBA 10/2019 - 02/2002
2	fibrin fragment D (D-dimer)IBA 01/2018 - 01/2005
2	Creatine Kinase (Creatine Phosphokinase)IBA 01/2018 - 09/2011
2	GadoliniumIBA 09/2017 - 01/2011
2	AntibodiesIBA 01/2017 - 01/2015
2	Anticonvulsants (Antiepileptic Drugs)IBA 11/2013 - 04/2009
2	InterferonsIBA 01/2012 - 01/2004
2	AntigensIBA 03/2011 - 05/2002
2	DNA-Binding Proteins (DNA Binding Protein)IBA 03/2011 - 01/2009
2	Amyloid beta-PeptidesIBA 08/2010 - 12/2009
2	Pharmaceutical PreparationsIBA 03/2010 - 10/2009
2	Indicators and Reagents (Reagents)IBA 02/2010 - 02/2008
2	CytokinesIBA 11/2009 - 01/2006
2	Interferon-alpha (Interferon Alfa)IBA 08/2007 - 01/2004
1	Antihypertensive Agents (Antihypertensives)IBA 10/2021
1	Dihydrotachysterol (AT 10)IBA 09/2020
1	Macrophage Colony-Stimulating FactorIBA 01/2020
1	Protein AggregatesIBA 01/2019
1	mecobalamin (methylcobalamin)IBA 01/2019
1	Toll-Like Receptor 4IBA 01/2018
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2018
1	Interleukin-10 (Interleukin 10)IBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	3-Iodobenzylguanidine (Iobenguane)IBA 01/2017
1	Levodopa (L Dopa)FDA LinkGeneric 01/2017
1	proadrenomedullinIBA 01/2017
1	CollagenIBA 12/2016

Therapy/Procedure

10	Therapeutics 12/2022 - 01/2004
2	Immunotherapy 01/2017 - 11/2005
2	Activities of Daily Living (ADL) 12/2013 - 03/2007
2	Radiotherapy 04/2011 - 08/2009
1	Secondary Prevention 09/2020
1	Microvascular Decompression Surgery 11/2017